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Aldosterone, Serum
Ordering Recommendation
New York DOH Approval Status
Specimen Required
Collect midmorning after patient has been sitting, standing or walking for at least 2 hours and seated for 5-15 minutes. Refer to the Additional Technical Information for specific patient preparation recommendations.
Serum Separator Tube (SST) or Plain Red.
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Frozen.
EDTA plasma.
After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
Effective May 16, 2011
| Age |
Posture Unspecified |
Supine |
Upright |
|---|---|---|---|
| 0-6 days | 5.0-102.0 ng/dL | ||
| 1-3 weeks | 6.0-179.0 ng/dL | ||
| 1-11 months | 7.0-99.0 ng/dL | ||
| 1-2 years | 7.0-93.0 ng/dL | ||
| 3-10 years | 4.0-44.0 ng/dL | ||
| 11-14 years | 4.0-31.0 ng/dL | ||
| 15 years and older | Less than or equal to 31.0 ng/dL | Less than or equal to 16.0 ng/dL | 4.0-31.0 ng/dL |
Interpretive Data
Normal serum levels of aldosterone are dependent on the sodium intake and whether the patient is upright or supine. High sodium intake will tend to suppress serum aldosterone, whereas low sodium intake will elevate serum aldosterone. The reference intervals for serum aldosterone are based on normal sodium intake.
FDA
Note
Refer to the Additional Technical Information for Endocrine Society recommendations for patient preparation, specimen collection, medications for hypertension control during confirmatory testing for primary aldosteronism, and factors that may lead to false-positive or false-negative aldosterone-renin ratio (ARR) results.
Hotline History
CPT Codes
82088
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0070015 | Aldosterone | 1763-2 |
Aliases
- Aldosterone, S
- serum aldosterone
